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Acknowledgements
Williamson ether
SMARTS
: [#6;$([#6]~[#6]);!$([#6]=O):2][#8;H1:3].[Cl,Br,I][#6;H2;$([#6]~[#6]):4]>>[CH2:4][O:3][#6:2]
Conditions
Reactant 1:
Alcohol.
Reactant 2:
alkyl halide (Cl, Br, I).
R1, R2
: ar, alkyl.
References
Williamson, A.
Ann. Chem. Pharm.
,
1851
, 77, 37–49.
Williamson, A. W. Q.
J. Chem. Soc.
,
1852
, 4, 229
Other sources
Organic chemistry
Wikipedia