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Decarboxylative coupling
SMARTS
: [c;$(c1[c;$(c[C,S,N](=[OD1])[*;R0;!OH1])]cccc1):1][C;$(C(=O)[O;H1])].[c;$(c1aaccc1):2][Cl,Br,I]>>[c:1][c:2]
Conditions
Reactant 1:
carboxylic acid.
Reactant 2:
aryl halide.
A
: C, N.
R1
: aryl.
X
: Cl, Br, I.
References
R. Shang, L. Riu,
Sci China Chem
,
2011
, 54, 1670-1687.
Other sources
Wikipedia