Phthalazinone
SMARTS: [c;r6:1](-[C;$(C=O):6]-[OH1]):[c;r6:2]-[C;H1,$(C-C):3]=[OD1].[NH2:4]-[NH1;$(N-[#6]);!$(NC=[O,S,N]):5]>>[c:1]1:[c:2]-[C:3]=[N:4]-[N:5]-[C:6]-1
Conditions
Reactant 1:
Reactant 2: hydrazine.
R1: H, alkyl. R2: carbon, but not C=O, C=N, C=S.
References
Akiko Sugimoto , Hiromichi Tanaka , Yukuo Eguchi , Shigeru Ito , Yoshimi Takashima , Masayuki Ishikawa, J. Med. Chem., 1984, 27, 1300–1305.