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Thiazole
SMARTS
: [#6:6]-[C;R0:1](=[OD1])-[CH1;R0:5](-[#6:7])-[*;#17,#35,#53].[NH2:2]-[C:3]=[SD1:4]>>[c:1]2(-[#6:6]):[n:2]:[c:3]:[s:4][c:5]([#6:7]):2
Conditions
Reactant 1:
halogenated ketone.
Reactant 2:
thioamide.
R1, R2
= alkyl.
R3
= alkyl, allyl, H.
X
= Cl, Br, I.
Other sources
Organic chemistry